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Summary
Paul Schumacker received his B.S. and M.Eng. degrees in biomedical engineering from Rensselaer Polytechnic Institute in Troy, NY. He then earned a PhD degree in the Department of Physiology at Albany Medical College, working in the laboratory of Dr. Thomas M. Saba. He completed a postdoctoral fellowship in the Section of Pulmonary Physiology at U.C. San Diego, working in the laboratory of Drs. John West and Peter Wagner. In 1983 he was recruited to the Pulmonary and Critical Care Section in the Department of Medicine at the University of Chicago. There, he was promoted to Assistant Professor in 1987, Associate Professor in 1989, and Professor with tenure in 1994. From 1995-2001 he served as the Chairman of the Comparative Medicine and Pathology Committee. In 2004 he was recruited to the Neonatology Division in the Department of Pediatrics at Northwestern University where he is Director of Neonatology Research, and Children’s Memorial Medical Center. In 2005 was named as the first Patrick M. Magoon Professor in Neonatology Research.
| Current Institution | Northwestern University |
| Current School | Feinberg School of Medicine |
| Department | Pediatrics, Cell and Molecular Biology and Medicine-Pulmonary |
| Disciplines | |
| Address | Morton Building Room 4-685, 310 E Superior Chicago Illinois 60611 United States Phone: 312-503-1475 |
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Education
Albany Medical College
Ph.D.,
Physiology
(1980)
Rensselaer Polytechnic Institute
M.Eng.,
biomedical engineering
Rensselaer Polytechnic Institute
B.S.
Work Experience
Professor
Feinberg School of Medicine, Northwestern University
Chairman of the Comparative Medicine and Pathology Committee
Feinberg School of Medicine, Northwestern University
Director of Neonatology Research, and Children’s Memorial Medical Center
Feinberg School of Medicine, Northwestern University
Patrick M. Magoon Professor in Neonatology Research
Feinberg School of Medicine, Northwestern University
Achievements
General
Publication Summary
Pubmed Publications
- Synthesis enables identification of the cellular target of leucascandrolide A and neopeltolide. Ulanovskaya OA, Janjic J, Suzuki M, Sabharwal SS, Schumacker PT, Kron SJ, Kozmin SA Nature chemical biology 2008 Jul; 4(7):418-24 PMID: 18516048
- Hypoxia inducible factor-alpha activation in lymphoma and relationship to the thioredoxin family. Evens AM, Schumacker PT, Helenowski IB, Singh AT, Dokic D, Keswani A, Kordeluk E, Raji A, Winter JN, Jovanovic BD, Holmgren A, Nelson BP, Gordon LI British journal of haematology 2008 May; 141(5):676-80 PMID: 18422776
- Role of hypoxia-inducible factor in cell survival during myocardial ischemia-reperfusion. Loor G, Schumacker PT Cell death and differentiation 2008 Apr; 15(4):686-90 PMID: 18259200
- AMP-activated protein kinase regulates CO2-induced alveolar epithelial dysfunction in rats and human cells by promoting Na,K-ATPase endocytosis. Vadász I, Dada LA, Briva A, Trejo HE, Welch LC, Chen J, Tóth PT, Lecuona E, Witters LA, Schumacker PT, Chandel NS, Seeger W, Sznajder JI The Journal of clinical investigation 2008 Feb; 118(2):752-62 PMID: 18188452
- Hyperoxia increases phosphodiesterase 5 expression and activity in ovine fetal pulmonary artery smooth muscle cells. Farrow KN, Groh BS, Schumacker PT, Lakshminrusimha S, Czech L, Gugino SF, Russell JA, Steinhorn RH Circulation research 2008 Feb 1; 102(2):226-33 PMID: 17991881
- Loss of the SdhB, but Not the SdhA, subunit of complex II triggers reactive oxygen species-dependent hypoxia-inducible factor activation and tumorigenesis. Guzy RD, Sharma B, Bell E, Chandel NS, Schumacker PT Molecular and cellular biology 2008 Jan; 28(2):718-31 PMID: 17967865
- Oxygen sensing in hypoxic pulmonary vasoconstriction: using new tools to answer an age-old question. Waypa GB, Schumacker PT Experimental physiology 2008 Jan; 93(1):133-8 PMID: 17993507
- BNIP3 is an RB/E2F target gene required for hypoxia-induced autophagy. Tracy K, Dibling BC, Spike BT, Knabb JR, Schumacker P, Macleod KF Molecular and cellular biology 2007 Sep; 27(17):6229-42 PMID: 17576813
- Mitochondrial complex III is required for hypoxia-induced ROS production and gene transcription in yeast. Guzy RD, Mack MM, Schumacker PT Antioxidants & redox signaling 2007 Sep; 9(9):1317-28 PMID: 17627464
- Nitric oxide during ischemia attenuates oxidant stress and cell death during ischemia and reperfusion in cardiomyocytes. Iwase H, Robin E, Guzy RD, Mungai PT, Vanden Hoek TL, Chandel NS, Levraut J, Schumacker PT Free radical biology & medicine 2007 Aug 15; 43(4):590-9 PMID: 17640569
- Mitochondrial reactive oxygen species trigger hypoxia-inducible factor-dependent extension of the replicative life span during hypoxia. Bell EL, Klimova TA, Eisenbart J, Schumacker PT, Chandel NS Molecular and cellular biology 2007 Aug; 27(16):5737-45 PMID: 17562866
- Oxidant stress during simulated ischemia primes cardiomyocytes for cell death during reperfusion. Robin E, Guzy RD, Loor G, Iwase H, Waypa GB, Marks JD, Hoek TL, Schumacker PT The Journal of biological chemistry 2007 Jun 29; 282(26):19133-43 PMID: 17488710
- Hypoxic conformance of metabolism in primary rat hepatocytes: a model of hepatic hibernation. Subramanian RM, Chandel N, Budinger GR, Schumacker PT Hepatology (Baltimore, Md.) 2007 Feb; 45(2):455-64 PMID: 17366663
Books
Other Publications
