Selected Publications

• Zhou Y, Wubneh H, Schwarz C, Landweber LF. (2011) A chimeric chromosome in the ciliate Oxytricha resulting from duplication. J Mol Evol. Oct 22. [Epub ahead of print]
• Jung S, Swart EC, Minx PJ, Magrini V, Mardis ER, Landweber LF, Eddy SR. (2011) Exploiting Oxytricha trifallax nanochromosomes to screen for non-coding RNA genes. Nucleic Acids Res. 39: 7529-7547.  
• Nowacki M, Haye JE, Fang W, Vijayan V, Landweber LF. (2010) RNA-mediated epigenetic regulation of DNA copy number. Proc Natl Acad Sci. 107: 22140-22144. 
• Nowacki M, Landweber LF. (2009) Epigenetic inheritance in ciliates. Curr Opin Microbiol. 12: 638-643.  
• Nowacki M, Higgins BP, Maquilan GM, Swart EC, Doak TG, Landweber LF. (2009) A functional role for transposases in a large eukaryotic genome. Science 324: 935-938.  
• Nowacki M, Vijayan V, Zhou Y, Schotanus K, Doak TG, Landweber LF. (2007) RNA-mediated epigenetic programming of a genome-rearrangement pathway. Nature 451: 153-158.  
• Landweber LF. (2007) Genetics. Why genomes in pieces? Science 318: 405-407.  
• Zhou Y, Landweber LF. (2007) BLASTO: a tool for searching orthologous groups. Nucl Acids Res 35: W678-682.  
• Liang H, Landweber LF. (2007) Hypothesis: RNA editing of microRNA target sites in humans? RNA 13: 463-467.  
• Liang H, Zhou W, Landweber LF. (2006) SWAKK: a web server for detecting positive selection in proteins using a sliding window substitution rate analysis. Nucl Acids Res 34: W382-384.  
• Cavalcanti AR, Stover NA, Landweber LF. (2006) On the paucity of duplicated genes in Caenorhabditis elegans operons. J Mol Evol 62: 765-771.  
• Liag H, Landweber LF. (2006) A genome-wide study of dual coding regions in human alternatively spliced genes. Genome Res 16: 190-196.  
• Chang WJ, Kuo S, Landweber LF. (2006) A new scrambled gene in the ciliate Uroleptus. Gene 368: 72-77.  
• Wong LC, Landweber LF. (2006) Evolution of programmed DNA rearrangements in a scrambled gene. Mol Biol Evol 23: 756-763.  
• McFarland CP, Chang WJ, Kuo S, Landweber LF. (2006) Conserved linkage of two genes on the same macronuclear chromosome in spirotrichous ciliates. Chromosoma 115: 129-138.  
• Chang WJ, Bryson PD, Liang H, Shin MK, Landweber LF. (2005) The evolutionary origin of a complex scrambled gene. Proc Natl Acad Sci USA 102: 15149-15154.  
• Liang H, Landweber LF. (2005) Molecular mimicry: quantitative methods to study structural similarity between protein and RNA. 11: 1167-1172.  
• Livstone MS, van Noort D and Landweber LF. (2003) Molecular computing revisited: a Moore's Law? Trends Biotechnol 21: 98-101.  
• Horton TL, Landweber LF. (2002) Rewriting the information in DNA: RNA editing in kinetoplastids and myxomycetes. Curr Opin Microbiol 5: 620-626.  
• Lozupone CA, Knight RD, Landweber LF. (2001) The molecular basis of nuclear genetic code change in ciliates. Curr Biol 11: 65-74.  
• Landweber LF, Kuo TC, Curtis EA. (2000) Evolution and assembly of an extremely scrambled gene. Proc Natl Acad Sci USA 97: 3298-3303.  
• Faulhammer D, Cukras AR, Lipton RJ, Landweber LF. (2000) Molecular computation: RNA solutions to chess problems. Proc Natl Acad Sci USA 97: 1385-1389.  
• Knight RD, Freeland SJ, Landweber LF. (1999) Selection, history and chemistry: the three faces of the genetic code. Trends Biochem Sci 24: 241-247.  
• Freeland SJ, Knight RD, Landweber LF. (1999) Do proteins predate DNA? Science 286: 690-692.