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Amy Jo Marcano-Reik
Post-Doctoral Researcher: Bioethics, Cleveland Clinic
Post-Doctoral Researcher: Center for Genetic Research Ethics & Law, Case Western Reserve University
Post-Doctoral Researcher: Center for Genetic Research Ethics & Law, Case Western Reserve University
Cleveland Clinic
Summary
Education:
2004-2011:
Ph.D. Interdisciplinary Studies - Neural Systems and Development
M.A. Psychology – Behavioral and Cognitive Neuroscience
University of Iowa, Iowa City, Iowa, USA
Pre-Doctoral Dean's Merit Fellow
2000-2003:
B.S. Neuroscience and Psychology, Cum Laude
Baldwin-Wallace College (Baldwin Wallace University as of 07/2012), Berea, Ohio, USA
Baldwin-Wallace Dean’s, Founder’s, Multicultural, Scholar’s, and Trustee’s Scholar
Statement:
For over a decade, my educational and research training have focused on epigenetic influences that contribute to central nervous system development, organization, and functional recovery after acute and chronic injury. Through interdisciplinary research and multi-systems examinations including behavioral and psychological, neurological, molecular/cellular, ethical, and computational analyses, I have examined complex brain-behavior interactions that have provided me with a better understanding of, and deeper appreciation for, dynamical systems and translational issues regarding human health and behavior. My Doctoral research examined the effects of endogenous and exogenous sensorimotor processes on cortical recovery of function after damage or injury. Specifically, I identified a critical period of postnatal cortical development during which increased motor activity and external sensory input resulted in recovery of connectivity and function after brain injury (i.e., split-brain surgery) in some ages, but not others. My graduate work has been published in the journals, Behavioral Neuroscience and European Journal of Neuroscience. During the pursuit of my Bachelors and Masters degrees, I conducted a series of experiments and analyses to assess neural and environmental factors that contribute to recovery of motor function and coordinative locomotor capabilities after spinal cord injury or damage. I augmented my training in central and peripheral nervous system examination through a laboratory and clinic training workshop offered by The Ohio State University (OSU) Spinal Cord Injury Research Training Program supported by the National Institutes of Neurological Disorders and Stroke (NINDS) and the Christopher Reeve Foundation.
My current Post-Doctoral research intersects the neurological and psychological sciences with ethical, legal, and social issues. Employing a mixed-methodological approach, I have spent the last year examining research partnerships involving patient-advocacy organizations representing rare genetic conditions (e.g., Muscular Dystrophy Association). I recently developed a survey instrument to assess clinical investigators’ views and experiences regarding their collaborative research experience with patient-advocacy groups and original databases to further understand the role of these research partnerships in biomedical research. Our work has been submitted for publication consideration to the Journal of Medical Ethics.
Due to my unique educational and professional training in the neurosciences, psychological sciences, bioethics, and clinical research domains, my research continues to explore and elucidate various epigenetic factors that contribute to development of and improvements in health and behavior.
| Current Institution | Cleveland Clinic |
| Current School | Case Western Reserve University |
| Department | Department of Bioethics and Center for Genetic Research Ethics and Law |
| Disciplines | |
| Address | 9500 Euclid Avenue Cleveland Ohio 44195 United States Phone: 216.636.2405 |
Website Profile viewed 1364 times
Education
University of Iowa
Ph.D., Interdisciplinary Studies - Neural Systems and Development,
Psychology
(Aug 2004 - Dec 2011)
Baldwin-Wallace College (Baldwin-Wallace University as of 07/2012)
B.S. with Honors, Neuroscience and Psychology,
Neuroscience, Psychology, and Chemistry
(Aug 2000 - Dec 2003)
Work Experience
Post-Doctoral Researcher
Cleveland Clinic and Case Western Reserve University
(Feb 2011 - Present)
Department of Bioethics, Cleveland Clinic; Center for Genetic Research Ethics and Law (CGREAL), Case Western Reserve University
Achievements
General
Publication Summary
Publications
Peer-reviewed Journal Articles:
- Sharp, R.S., Marcano-Reik, A.J., Landy, D.C., Brinich, M.A., Colten, M.E., & Horn, L.E. (Submitted to the Journal of Medical Ethics). How disease advocacy organizations contribute to clinical research: A survey of involvement.
- Marcano-Reik, A.J., Prasad, T., Weiner, J.A., & Blumberg, M.S. (2010). An abrupt developmental shift in callosal modulation of sleep-related spindle bursts coincides with the emergence of excitatory-inhibitory balance and a reduction of somatosensory cortical plasticity. Behavioral Neuroscience, Oct; 124 (5): 600-611.
- Marcano-Reik, A. J.& Blumberg, M. S. (2008). The corpus callosum modulates spindle-burst activity within homotopic regions of somatosensory cortex in newborn rats. European Journal of Neuroscience, Oct; 28 (8): 1457-1466.
Chapters and Scholarly Entries:
- Marcano-Reik, A.J. (in press). Acute Illness. Encyclopedia of Behavioral Medicine. Springer Publishers.
- Marcano-Reik, A.J. (in press). Angiography/Angioplasty. Encyclopedia of Behavioral Medicine. Springer Publishers.
- Marcano-Reik, A.J. (in press). Antihypertensive Medications. Encyclopedia of Behavioral Medicine. Springer Publishers.
- Marcano-Reik, A.J. (in press). Clinical Trial. Encyclopedia of Behavioral Medicine. Springer Publishers.
- Marcano-Reik, A.J.& Blumberg, M.S. (2010). What is Neuroscience? Corsini’s Encyclopedia of Psychology, 4th Edition. John Wiley & Sons, Inc. Hoboken, NJ.
Published Abstracts:
- Marcano-Reik, A.J., Prasad, T., Weiner, J.A., & Blumberg, M.S. (2010). An abrupt developmental shift in callosal modulation of sleep-related spindle bursts coincides with the emergence of excitatory-inhibitory balance and a reduction of somatosensory cortical plasticity.Developmental Psychobiology.
- Marcano-Reik, A.J.(2009). Developmental plasticity after acute and chronic transection of the corpus callosum: Evidence for recovery of function and GABAergic inhibition during the early postnatal period. Developmental Psychobiology, 51 (7), 593.
- Marcano-Reik, A.J. & Blumberg, M.S. (2008). The corpus callosum modulates spindle-burst activity within homotopic regions of somatosensory cortex in newborn rats. Developmental Psychobiology, 50 (7), 736.
- Marcano-Reik, A.J., Todd, W.D., Seelke, A.M.H, & Blumberg, M.S. (2007). Development, state-dependence, and somatotopic organization of neocortical activity during the early postnatal period in rats. Developmental Psychobiology, 49 (7), 734.
- Seelke, A.M.H, Marcano-Reik, A.J., & Blumberg, M.S. (2007). The infant rat neocortex exhibits multiple forms of state-dependent activity before the emergence of delta waves. Developmental Psychobiology, 49 (7), 734.
- Brumley, M.R., Marcano-Reik, A.J., & Robinson, S.R. (2005). Perinatal development of hindlimb coordination in the rat. I. Postnatal experience potentiates 5-HT-induced stepping at term [Abstract]. Developmental Psychobiology, 47 (4), 421.
- Marcano-Reik, A.J., Brumley, M.R., & Robinson, S.R. (2005). Perinatal development of hindlimb coordination in the rat. II. Motor learning modifies 5-HT-induced stepping [Abstract]. Developmental Psychobiology, 47 (4), 438.
- Marcano-Reik, A.J., Woller, S.A., & Robinson, S.R. (2005). Hindlimb coordination after in-phase or antiphase yoke training in the infant rat: Developmental changes and effects of training on quipazine-induced stepping [Abstract]. Poster presented at the annual meeting of the Society for Neuroscience (Program No. 603.18). http://sfn.scholarone.com/itin2005/index.html.
- Robinson, S.R., Marcano-Reik, A.J., Brumley, M.R., & Kleven, G.A. (2005). Perinatal development of hindlimb coordination in the rat. III. Do conditions in utero reinforce antiphase movement? [Abstract]. Developmental Psychobiology, 47 (4), 445.
- Marcano-Reik, A.J.& Robinson, S.R. (2004). Motor learning and memory after interlimb yoke training in the rat fetus is spinally mediated [Abstract]. Poster presented at the annual meeting of the Society for Neuroscience (Program No. 946.7) http://sfn.scholarone.com/itin2004/index.html.
- Marcano, A.J.& Robinson, S.R. (2003). Retention of hindlimb motor coordination after mid-thoracic spinal transection in the rat fetus [Abstract]. Developmental Psychobiology, 43 (3), 265.
- Menge, J. A., Marcano, A.J., Coryell, V.T., & Alberts, J.R. (2002). Effect of birth fluid on parental responses of adult spiny mice (Acomys cahirinus). Developmental Psychobiology, 41 (3), 314.
Books
Other Publications
